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1

Mode of action of natural and synthetic drugs against Trypanosoma cruzi and their interaction with the mammalian host

Juan Diego Maya, Bruce K. Cassels, Patricio Iturriaga-Vásquez, Jorge Ferreira, Mario Faúndez, Norbel Galanti, Arturo Ferreira, Antonio Morello

Journal:

Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology

Year:

2007

Language:

english

File:

PDF, 494 KB

english, 2007

2

Lack of correlation between cholinergic-induced changes in chemosensory activity and dopamine release from the cat carotid body in vitro

Rodrigo Iturriaga, Julio Alcayaga, Patricio Zapata

Journal:

Year:

2000

Language:

english

File:

PDF, 229 KB

english, 2000

3

Characterization of a novel Drosophila SERT mutant: insights on the contribution of the serotonin neural system to behaviors

Hidalgo, Sergio, Molina-Mateo, Daniela, Escobedo, Pía, Zarate, Rafaella V, Fritz, Elsa, Fierro, Angélica, Pérez, Edwin G., Iturriaga-Vasquez, Patricio, Reyes-Parada, Miguel, Varas, Rodrigo, Fuenzalida

Journal:

ACS Chemical Neuroscience

Year:

2017

Language:

english

File:

PDF, 1.46 MB

english, 2017

4

Existence of solution for quasilinear equations involving local conditions

Cerda, Patricio, Iturriaga, Leonelo

Journal:

Proceedings of the Royal Society of Edinburgh Section A Mathematics

Year:

2019

File:

PDF, 209 KB

2019

5

Synthesis of Novel Nicotinic Ligands with Multimodal Action: Targeting Acetylcholine α4β2, Dopamine and Serotonin Transporters

González-Gutiérrez, Juan Pablo, Pessoa-Mahana, Hernán Armando, Iturriaga-Vásquez, Patricio Ernesto, Reyes-Parada, Miguel Iván, Guerra-Díaz, Nicolas Esteban, Hodar-Salazar, Martin, Viscarra, Franco, Pa

Journal:

Year:

2019

Language:

english

File:

PDF, 3.02 MB

english, 2019

6

Aporphine metho salts as neuronal nicotinic acetylcholine receptor blockers

Patricio Iturriaga-Vásquez, Edwin G. Pérez, E. Yvonne Slater, Isabel Bermúdez, Bruce K. Cassels

Journal:

Bioorganic & Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 187 KB

english, 2007

7

Naphthylisopropylamine and N-benzylamphetamine derivatives as monoamine oxidase inhibitors

Marcelo Vilches-Herrera, Juan Miranda-Sepúlveda, Marco Rebolledo-Fuentes, Angélica Fierro, Susan Lühr, Patricio Iturriaga-Vasquez, Bruce K. Cassels, Miguel Reyes-Parada

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 497 KB

english, 2009

8

2-Arylthiomorpholine derivatives as potent and selective monoamine oxidase B inhibitors

Susan Lühr, Marcelo Vilches-Herrera, Angélica Fierro, Rona R. Ramsay, Dale E. Edmondson, Miguel Reyes-Parada, Bruce K. Cassels, Patricio Iturriaga-Vásquez

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 542 KB

english, 2010

9

Electrochemical preparation of conductive films of tetrapyridylporphyrins coordinated to four [Ru(5-NO2-phen)2Cl]+ groups

Paulina A. Dreyse, Mauricio A. Isaacs, Patricio E. Iturriaga, Diego A. Villagra, María J. Aguirre, Clifford P. Kubiak, Starla D. Glover, John C. Goeltz

Journal:

Journal of Electroanalytical Chemistry

Year:

2010

Language:

english

File:

PDF, 764 KB

english, 2010

10

Erratum to: Aminochrome Induces Disruption of Actin, Alpha-, and Beta-Tubulin Cytoskeleton Networks in Substantia-Nigra-Derived Cell Line

Irmgard Paris, Carolina Perez-Pastene, Sergio Cardenas, Patricio Iturriaga-Vasquez, Patricia Muñoz, Eduardo Couve, Pablo Caviedes, Juan Segura-Aguilar

Journal:

Neurotoxicity Research

Year:

2010

File:

PDF, 86 KB

2010

11

Evaluation of benzyltetrahydroisoquinolines as ligands for neuronal nicotinic acetylcholine receptors

Richard Exley, Patricio Iturriaga-Vásquez, Ronald J Lukas, Emanuele Sher, Bruce K Cassels, Isabel Bermudez

Journal:

British Journal of Pharmacology

Year:

2005

Language:

english

File:

PDF, 388 KB

english, 2005

12

Electrophysiological characterization of nicotinic acetylcholine receptors in cat petrosal ganglion neurons in culture: Effects of cytisine and its bromo derivatives

Rodrigo Varas, Viviana Valdés, Patricio Iturriaga-Vásquez, Bruce K. Cassels, Rodrigo Iturriaga, Julio Alcayaga

Journal:

Year:

2006

Language:

english

File:

PDF, 194 KB

english, 2006

13

C3-halogenation of cytisine generates potent and efficacious nicotinic receptor agonists

J. Andrés Abin-Carriquiry, Merja H. Voutilainen, Jacques Barik, Bruce K. Cassels, Patricio Iturriaga-Vásquez, Isabel Bermudez, Claudia Durand, Federico Dajas, Susan Wonnacott

Journal:

European Journal of Pharmacology

Year:

2006

Language:

english

File:

PDF, 606 KB

english, 2006

14

Catecholamine release from isolated sensory neurons of cat petrosal ganglia in tissue culture

Rodrigo Iturriaga, Verónica Cerpa, Patricio Zapata, Julio Alcayaga

Journal:

Year:

2003

Language:

english

File:

PDF, 309 KB

english, 2003

15

Selective activation of carotid nerve fibers by acetylcholine applied to the cat petrosal ganglion in vitro

Julio Alcayaga, Rodrigo Iturriaga, Rodrigo Varas, Jorge Arroyo, Patricio Zapata

Journal:

Year:

1998

Language:

english

File:

PDF, 277 KB

english, 1998

16

Dopamine modulates carotid nerve responses induced by acetylcholine on the cat petrosal ganglion in vitro

Julio Alcayaga, Rodrigo Varas, Jorge Arroyo, Rodrigo Iturriaga, Patricio Zapata

Journal:

Year:

1999

Language:

english

File:

PDF, 236 KB

english, 1999

17

Responses to hypoxia of petrosal ganglia in vitro

Julio Alcayaga, Rodrigo Varas, Jorge Arroyo, Rodrigo Iturriaga, Patricio Zapata

Journal:

Year:

1999

Language:

english

File:

PDF, 277 KB

english, 1999

18

Functional expression of the α7 and α4-containing nicotinic acetylcholine receptors on the neonatal rat carotid body

Rodrigo C. Meza, Fernando C. Ortiz, Eduardo Bravo, Patricio Iturriaga-Vásquez, Jaime L. Eugenín, Rodrigo Varas

Journal:

Neurochemistry International

Year:

2012

Language:

english

File:

PDF, 613 KB

english, 2012

19

Adenosine triphosphate-induced peripheral nerve discharges generated from the cat petrosal ganglion in vitro

Julio Alcayaga, Verónica Cerpa, Mauricio Retamal, Jorge Arroyo, Rodrigo Iturriaga, Patricio Zapata

Journal:

Neuroscience Letters

Year:

2000

Language:

english

File:

PDF, 152 KB

english, 2000

20

4-Methylthioamphetamine Increases Dopamine in the Rat Striatum and has Rewarding Effects In Vivo

Ramón Sotomayor-Zárate, Gabriel Quiroz, Katherine A. Araya, Jorge Abarca, María R. Ibáñez, Alejandro Montecinos, Carlos Guajardo, Gabriel Núñez, Angélica Fierro, Pablo R. Moya, Patricio Iturriaga-Vásq

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2012

Language:

english

File:

PDF, 351 KB

english, 2012

21

Effect of insular cortex inactivation on autonomic and behavioral responses to acute hypoxia in conscious rats

Casanova, Jose Patricio, Contreras, Marco, Moya, Esteban A., Torrealba, Fernando, Iturriaga, Rodrigo

Journal:

Behavioural Brain Research

Year:

2013

Language:

english

File:

PDF, 1.24 MB

english, 2013

22

Design, Synthesis, Binding and Docking-Based 3D-QSAR Studies of 2-Pyridylbenzimidazoles—A New Family of High Affinity CB1 Cannabinoid Ligands

Mella-Raipán, Jaime, Lagos, Carlos, Recabarren-Gajardo, Gonzalo, Espinosa-Bustos, Christian, Romero-Parra, Javier, Pessoa-Mahana, Hernán, Iturriaga-Vásquez, Patricio, Pessoa-Mahana, Carlos

Journal:

Year:

2013

Language:

english

File:

PDF, 729 KB

english, 2013

23

Synthesis, docking and pharmacological evaluation of novel homo- and hetero-bis 3-piperazinylpropylindole derivatives at SERT and 5-HT1A receptor

Pessoa-Mahana, Hernán, González-Lira, Christian, Fierro, Angélica, Zapata-Torres, Gerald, Pessoa-Mahana, C. David, Ortiz-Severin, Javiera, Iturriaga-Vásquez, Patricio, Reyes-Parada, Miguel, Silva-Matu

Journal:

Bioorganic & Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 1.58 MB

english, 2013

24

Experimental and theoretical study on the oxidation mechanism of dopamine in n-octyl pyridinium based ionic liquids–carbon paste modified electrodes

Díaz, Carlos, García, Camilo, Iturriaga-Vásquez, Patricio, Aguirre, Maria Jesús, Muena, Juan Pablo, Contreras, Renato, Ormazábal-Toledo, Rodrigo, Isaacs, Mauricio

Journal:

Electrochimica Acta

Year:

2013

Language:

english

File:

PDF, 1.53 MB

english, 2013

25

Simplified Tetrandrine Congeners as Possible Antihypertensive Agents with a Dual Mechanism of Action

Iturriaga-Vásquez, Patricio, Miquel, Raquel, Ivorra, M. Dolores, D'Ocon, M. Pilar, Cassels, Bruce K.

Journal:

Journal of Natural Products

Year:

2003

Language:

english

File:

PDF, 66 KB

english, 2003

26

Non-equivalent Ligand Selectivity of Agonist Sites in (α4β2) 2 α4 Nicotinic Acetylcholine Receptors

Mazzaferro, Simone, Gasparri, Federica, New, Karina, Alcaino, Constanza, Faundez, Manuel, Iturriaga Vasquez, Patricio, Vijayan, Ranjit, Biggin, Philip C., Bermudez, Isabel

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.47 MB

english, 2014

27

Improving Amphetamine Therapeutic Selectivity: N,N -dimethyl-MTA has Dopaminergic Effects and does not Produce Aortic Contraction

Sotomayor-Zárate, Ramón, Jara, Pablo, Araos, Patricio, Vinet, Raúl, Quiroz, Gabriel, Renard, Georgina M., Espinosa, Pedro, Hurtado-Guzmán, Claudio, Moya, Pablo R., Iturriaga-Vásquez, Patricio, Gysling

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2014

Language:

english

File:

PDF, 208 KB

english, 2014

28

Synthesis and Biological Screening of Novel Indolalkyl Arenes Targeting the Serotonine Transporter

Ojeda-Gómez, Claudia, Pessoa-Mahana, Hernán, Iturriaga-Vásquez, Patricio, Pessoa-Mahana, Carlos David, Recabarren-Gajardo, Gonzalo, Méndez-Rojas, Claudio

Journal:

Archiv der Pharmazie

Year:

2014

Language:

english

File:

PDF, 254 KB

english, 2014

29

Design, Synthesis, Biological Evaluation and Binding Mode Modeling of Benzimidazole Derivatives Targeting the Cannabinoid Receptor Type 1

Espinosa-Bustos, Christian, Lagos, Carlos F., Romero-Parra, Javier, Zárate, Ana M., Mella-Raipán, Jaime, Pessoa-Mahana, Hernán, Recabarren-Gajardo, Gonzalo, Iturriaga-Vásquez, Patricio, Tapia, Ricardo

Journal:

Archiv der Pharmazie

Year:

2015

Language:

english

File:

PDF, 943 KB

english, 2015

30

Multiple binding sites in the nicotinic acetylcholine receptors: An opportunity for polypharmacolgy

Iturriaga-Vásquez, Patricio, Alzate-Morales, Jans, Bermudez, Isabel, Varas, Rodrigo, Reyes-Parada, Miguel

Journal:

Pharmacological Research

Year:

2015

Language:

english

File:

PDF, 2.43 MB

english, 2015

31

Antioxidant and anti hyperglycemic role of wine grape powder in rats fed with a high fructose diet

Hernández-Salinas, Romina, Decap, Valerie, Leguina, Alberto, Cáceres, Patricio, Perez, Druso, Urquiaga, Ines, Iturriaga, Rodrigo, Velarde, Victoria

Journal:

Biological Research

Year:

2015

Language:

english

File:

PDF, 1.17 MB

english, 2015

32

β-Ionone as putative semiochemical suggested by ligand binding on an odorant-binding protein of Hylamorpha elegans and electroantennographic recordings

Venthur, Herbert, Zhou, Jing-Jiang, Mutis, Ana, Ceballos, Ricardo, Mella-Herrera, Rodrigo, Larama, Giovanni, Avila, Andrés, Iturriaga-Vásquez, Patricio, Faundez-Parraguez, Manuel, Alvear, Marysol, Qui

Journal:

Entomological Science

Year:

2016

Language:

english

File:

PDF, 513 KB

english, 2016

33

Synthesis, binding assays, cytotoxic activity and docking studies of benzimidazole and benzothiophene derivatives with selective affinity for the CB2 cannabinoid receptor

Romero-Parra, Javier, Mella-Raipan, Jaime, Palmieri, Vittoria, Allarà, Marco, Torres, Maria Jose, Pessoa-Mahana, Hernán, Iturriaga, Patricio, Escobar, Rossy, Faúndez, Mario, Di Marzo, Vincenzo, Pessoa

Journal:

European Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 982 KB

english, 2016

34

The development of novel polypharmacological agents targeting the multiple binding sites of nicotinic acetylcholine receptors

Reyes-Parada, Miguel, Iturriaga-Vasquez, Patricio

Journal:

Expert Opinion on Drug Discovery

Year:

2016

Language:

english

File:

PDF, 976 KB

english, 2016

35

Role of the Cys loop and transmembrane domain in the allosteric modulation of α4β2 nicotinic acetylcholine receptors

Alcaino, Constanza, Musgaard, Maria, Minguez, Teresa, Mazzaferro, Simone, Faundez, Manuel, Iturriaga-Vasquez, Patricio, Biggin, Philip C, Bermudez, Isabel

Journal:

Journal of Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 8.72 MB

english, 2016

36

Synthesis and Docking of Novel 3-Indolylpropyl Derivatives as New Polypharmacological Agents Displaying Affinity for 5-HT 1A R/SERT

Pessoa-Mahana, Hernán, Silva-Matus, Paul, Pessoa-Mahana, C. David, Chung, Hery, Iturriaga-Vásquez, Patricio, Quiroz, Gabriel, Möller-Acuña, Patricia, Zapata-Torres, Gerald, Saitz-Barría, Claudio, Aray

Journal:

Archiv der Pharmazie

Year:

2017

Language:

english

File:

PDF, 1.77 MB

english, 2017

37

Rhodolirium andicola : a new renewable source of alkaloids with acetylcholinesterase inhibitory activity, a study from nature to molecular docking

Moraga-Nicolás, Felipe, Jara, Claudia, Godoy, Ricardo, Iturriaga-Vásquez, Patricio, Venthur, Herbert, Quiroz, Andrés, Becerra, José, Mutis, Ana, Hormazábal, Emilio

Journal:

Revista Brasileira de Farmacognosia

Year:

2018

Language:

english

File:

PDF, 1.89 MB

english, 2018

38

Erysodine, a competitive antagonist at neuronal nicotinic acetylcholine receptors, decreases ethanol consumption in alcohol-preferring UChB rats

Quiroz, Gabriel, Guerra-Díaz, Nicolás, Iturriaga-Vásquez, Patricio, Rivera-Meza, Mario, Quintanilla, María Elena, Sotomayor-Zárate, Ramón

Journal:

Behavioural Brain Research

Year:

2018

Language:

english

File:

PDF, 626 KB

english, 2018

39

3D similarities between the binding sites of monoaminergic target proteins

Núñez-Vivanco, Gabriel, Fierro, Angélica, Moya, Pablo, Iturriaga-Vásquez, Patricio, Reyes-Parada, Miguel, Helmer-Citterich, Manuela

Journal:

Year:

2018

Language:

english

File:

PDF, 21.15 MB

english, 2018

40

STRUCTURAL REASSIGNMENT OF EPIERYTHRATIDINE, AN ALKALOID FROM Erythrinafusca, BASED ON NMR STUDIES AND COMPUTATIONAL METHODS

GARCÍA-BELTRÁN, OLIMPO, SOTO-DELGADO, JORGE, ITURRIAGA-VÁSQUEZ, PATRICIO, ARECHE, CARLOS, CASSELS, BRUCE K

Journal:

Journal of the Chilean Chemical Society

Year:

2012

Language:

english

File:

PDF, 576 KB

english, 2012

41

Galanthamine and other Amaryllidaceae related alkaloids are inhibitors of α7, α4β2 and α3β4 nicotinic acetylcholine receptors

Moraga-Nicolás, Felipe, Iturriaga-Vásquez, Patricio, Mutis, Ana, Hormazábal, Emilio, Bermúdez-Díaz, Isabel

Journal:

Revista Brasileira de Farmacognosia

Year:

2019

Language:

english

File:

PDF, 641 KB

english, 2019

42

Existence of solution for quasilinear equations involving local conditions

Cerda, Patricio, Iturriaga, Leonelo

Journal:

Proceedings of the Royal Society of Edinburgh Section A Mathematics

Year:

2019

Language:

english

File:

PDF, 209 KB

english, 2019

43

Amphetamine Derivatives as Monoamine Oxidase Inhibitors

Reyes-Parada, Miguel, Iturriaga-Vasquez, Patricio, Cassels, Bruce K.

Journal:

Frontiers in Pharmacology

Year:

2020

File:

PDF, 1.77 MB

2020

44

Synthesis, Docking, 3-D-Qsar, and Biological Assays of Novel Indole Derivatives Targeting Serotonin Transporter, Dopamine D2 Receptor, and Mao-A Enzyme: In the Pursuit for Potential Multitarget Directed Ligands

Cerda-Cavieres, Christopher, Quiroz, Gabriel, Iturriaga-VÃ¡squez, Patricio, RodrÃguez-Lavado, Julio, AlarcÃ³n-EspÃ³sito, JazmÃn, Saitz, Claudio, Pessoa-Mahana, Carlos D., Chung, Hery, Araya-Maturana

Journal:

Year:

2020

File:

PDF, 5.80 MB

2020

45

Pharmacological Characterization of 4-Methylthioamphetamine Derivatives

Guajardo, Fabrizzio G., VelÃ¡squez, Victoria B., Raby, Daniela, NÃºÃ±ez-Vivanco, Gabriel, Iturriaga-VÃ¡squez, Patricio, EspaÃ±a, Rodrigo A., Reyes-Parada, Miguel, Sotomayor-ZÃ¡rate, RamÃ³n

Journal:

Year:

2020

File:

PDF, 2.36 MB

2020

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